Moniliphenone
Application Notes
Moniliphenone was first isolated from Monilinia fructicola during a biosynthetic study of chloromonilicin, a novel growth self-inhibitor, by researchers at Yamagata University, Japan in 1986. Moniliphenone is a key intermediate in biosynthesis of the fungal xanthones belonging to the group of pinselin and its related metabolites. Moniliphenone is weakly active against a range of human tumor cell lines. Moniliphenone is a weak phytotoxin.
References
- Isolation of a key intermediate in xanthone biosynthesis from Monilinia fruticola. Kachi H. & Sassa T. Agric Biol Chem. 1986, 50, 1669.
- Cytotoxic xanthone–anthraquinone heterodimers from an unidentified fungus of the order Hypocreales (MSX 17022). Ayers S. et al. J Antibiot. 2012, 65, 3.
- Rabenchromenone and rabenzophenone, phytotoxic tetrasubstituted chromenone and hexasubstituted benzophenone constituents produced by the oak-decline-associated fungus Fimetariella rabenhorstii. Bashiri S. et al. J Nat Prod. 2020, 83, 447.