Epibenzomalvin E

Epibenzomalvin E

$195.00 - 0.50 mg

$685.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-E2360
CAS #
NA
Molecular Formula
C24H19N3O3
Molecular Weight
397.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Product Data Sheet

Application Notes

The benzomalvins are substance P inhibitors of human neurokinin NK1 receptors from Penicillium sp. The structure of epibenzolmalvin E as the (-) isomer of the benzomalvin E epimers was published in 2020. Little is known of the biological activity of benzomalvin E and its epimer, although it is reported to inhibit 2,3-dioxygenase.

References

  • Benzomalvins, new substance P inhibitors from a Penicillium sp. Sun H.H. et al J Antibiot. 1994, 47, 515.
  • (±) Benzomalvins E isolated from Penicillium sp. SYPF 8411 in the rhizosphere soil of Codonopsis clematidea. Feng Q-M. et al. Nat Prod Res. 2020, 34, 1884.
  • Benzomalvin E, an indoleamine 2,3-dioxygenase inhibitor isolated from Penicillium sp. FN070315. J Antibiot. 2012, 65, 4.

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