Desmethoxystreptonigrin, 10′-

Desmethoxystreptonigrin, 10′-

$287.00 - 0.50 mg

$1,005.00 - 2.50 mg

All prices in Australian dollars

CAS #
136803-89-9
Molecular Formula
C24H20N4O7
Molecular Weight
476.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Clear

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Application Notes

10'-Desmethoxystreptonigrin is a close analogue of streptonigrin produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has also been reported to have potent and broad spectrum antibacterial and antitumor activity.

References

  • 10'-desmethyloxystreptonigrin, a novel analog of streptonigrin. Liu W.C. et al., J. Antibiot. 1992, 45, 454.

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