Verlamelin B

Verlamelin B

$179.00 - 0.25 mg

$625.00 - 1 mg

All prices in Australian dollars

Code
BIA-V2940
CAS #
1619237-95-4
Molecular Formula
C44H69N7O11
Molecular Weight
872.06
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.
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Application Notes

Verlamelin B is a complex lipodepsipeptide antibiotic first isolated from Lecanicillium sp. by Nihira and co-workers at Mahidol University, Thailand in 2014. Verlamelin B is active against phytopathogenic fungi, including Aspergillus versicolor and Curvularia australiensis. Verlamelin B is also a potent inhibitor of Colletotrichum asianum (MIC 5-10 μg/mL). Verlamelin B is active against HSV-1 with an IC50 of 15.6 μM.

References

  • Cyclic lipodepsipeptides verlamelin A and B, isolated from entomopathogenic fungus Lecanicillium sp. Ishidoh K. et al. J Antibiot 2014, 67, 459.
  • Antifungal and Antiviral Cyclic Peptides from the Deep-Sea-Derived Fungus Simplicillium obclavatum EIODSF 020. Liang X. et al. J Ag Food Chem 2017, 65, 5114.
  • Peptides from the soft coral-associated fungus Simplicillium sp. SCSIO41209. Dai Y. et al. Phytochem 2018, 154, 56.

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