Anhydrotetracycline hydrochloride

Anhydrotetracycline hydrochloride

$91.00 - 1 mg

$319.00 - 5 mg

All prices in Australian dollars

CAS #
13803-65-1
Molecular Formula
C22H23ClN2O7
Molecular Weight
462.9
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Moderate water solubility.
Clear

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Application Notes

Anhydrotetracycline hydrochloride is a salt of a degradation product of tetracycline, formed by dehydration at the C6 position under acidic conditions to aromatise the B ring. Anhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, anhydrotetracycline is considered biologically active and is thought responsible for aspects of tetracycline toxicity.

References

  • Kinetics of concomitant degradation of tetracycline to epitetracycline, anhydrotetracycline, and epianhydrotetracycline in acid phosphate solution. Yuen P. H. & Sokoloski T.D. J. Pharm. Sci. 1977, 66, 1648.

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