Acarbose

Acarbose

$96.00 - 25 mg

$336.00 - 100 mg

All prices in Australian dollars

Synonyms
Amylostatin J, Bay g 5421, alpha-GHI
CAS #
56180-94-0
Molecular Formula
C25H43NO18
Molecular Weight
645.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in water with partial methanol, ethanol DMF and DMSO solubility.
Clear

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Application Notes

Acarbose is pseudo-oligosaccharide with a terminal C7-cyclitol patented in 1975 by Bayer. Acarbose is a component of the amylostatin complex produced by species of Actinoplanes and Streptomyces. Acarbose acts as a potent inhibitor of α-glucosidases and saccharases. Since 1990, acarbose has been used therapeutically for the treatment of type 2 diabetes.

References

  • Chemistry and Biochemistry of Microbial alpha-Glucosidase Inhibitors. Truscheit, E. et al., Angew. Chem. Int. Ed. Engl. 1981, 20, 744.
  • Acarbose. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential. Clissold S. P. &: Edwards C. Drugs. 1988, 35, 214.

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