Acarbose
Acarbose
$195.00 - 25 mg
$55.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-A1231
- Synonyms
- Amylostatin J, Bay g 5421, alpha-GHI
- CAS #
- 56180-94-0
- Molecular Formula
- C25H43NO18
- Molecular Weight
- 645.6
- Purity
- >95% by HPLC
- Long Term Storage
- Soluble in water with partial methanol, ethanol DMF and DMSO solubility.
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Application Notes
Acarbose is pseudo-oligosaccharide with a terminal C7-cyclitol patented in 1975 by Bayer. Acarbose is a component of the amylostatin complex produced by species of Actinoplanes and Streptomyces. Acarbose acts as a potent inhibitor of α-glucosidases and saccharases. Since 1990, acarbose has been used therapeutically for the treatment of type 2 diabetes.
References
- Chemistry and Biochemistry of Microbial alpha-Glucosidase Inhibitors. Truscheit, E. et al., Angew. Chem. Int. Ed. Engl. 1981, 20, 744.
- Acarbose. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential. Clissold S. P. &: Edwards C. Drugs. 1988, 35, 214.