Actinopyrone A

Actinopyrone A

$276.00 - 0.50 mg

$966.00 - 2.50 mg

All prices in Australian dollars

CAS #
88378-59-0
Molecular Formula
C25H36O4
Molecular Weight
400.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Clear

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Application Notes

Actinopyrone A is a gamma-pyrone compound isolated from a Streptomyces sp. It shows selective (>10E6 fold) and potent (MIC 0.0001 μg/ml) activity against Helicobacter pylori, the principal cause of peptic ulcer disease. Actinopyrone A was originally identified for its coronary vasodilating activity and weak activity against some Gram positive bacteria and dermatophytes.

References

  • Gamma-Pyrone compounds with selective and potent anti-Helicobacter pylori activity. Taniguchi M., et al., J. Antibiotics, 2000, 53, 844.
  • Actinopyrones A, B and C, new physiologically active substances. I. Producing organism, fermentation, isolation and biological properties. Yano K., et al., J. Antibiotics, 1986, 39, 32.
  • Actinopyrones A, B and C, new physiologically active substances. II. Physico-chemical properties and chemical structures. Yano K., et al., J. Antibiotics, 1986, 39, 38.

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