Trimethoxydictamnine, 5,7,8-

Trimethoxydictamnine, 5,7,8-

$232.00 - 1 mg

$813.00 - 5 mg

All prices in Australian dollars

Code
BIA-T1950
Synonyms
Acronycidine, 4,5,7,8-Tetramethoxyfuro[2,3-b]quinoline, NSC 30619
CAS #
521-43-7
Molecular Formula
C15H15NO5
Molecular Weight
289.28
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
Clear

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Application Notes

5,7,8-Trimethoxydictamnine (acronycidine) is a methoxy-substituted furoquinoline alkaloid isolated from Acronychia baueri and Melicope fareana by Price and colleagues at CSIRO, Australia, in 1950. 5,7,8-Trimethoxydictamnine was subsequently isolated from other Rutaceae found in Australia and the Asia Pacific region. 5,7,8-Trimethoxydictamnine is active against susceptible (HB3) and resistant (W-2) strains of Plasmodium falciparum with IC50 19.9 and 5.7 µg/mL, respectively.

References

  • Alkaloids of the Australian Rutaceae. The structure and reactions of acronycidine. Lahey F.N. et al. Aust J Sci Res Ser. A 1950, 3, 155. 
  • In vitro activities of furoquinoline and acridone alkaloids against Plasmodium falciparum. Basco L.K. et al. Antimicrob Agents Chemother. 1994, 38, 1169.

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