Trimethoxydictamnine, 5,7,8-
Trimethoxydictamnine, 5,7,8-
$255.00 - 1 mg
$895.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-T1950
- Synonyms
- Acronycidine, 4,5,7,8-Tetramethoxyfuro[2,3-b]quinoline, NSC 30619
- CAS #
- 521-43-7
- Molecular Formula
- C15H15NO5
- Molecular Weight
- 289.28
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in methanol or DMSO
Download Data Sheets
Application Notes
5,7,8-Trimethoxydictamnine (acronycidine) is a methoxy-substituted furoquinoline alkaloid isolated from Acronychia baueri and Melicope fareana by Price and colleagues at CSIRO, Australia, in 1950. 5,7,8-Trimethoxydictamnine was subsequently isolated from other Rutaceae found in Australia and the Asia Pacific region. 5,7,8-Trimethoxydictamnine is active against susceptible (HB3) and resistant (W-2) strains of Plasmodium falciparum with IC50 19.9 and 5.7 µg/mL, respectively.
References
- Alkaloids of the Australian Rutaceae. The structure and reactions of acronycidine. Lahey F.N. et al. Aust J Sci Res Ser. A 1950, 3, 155.
- In vitro activities of furoquinoline and acridone alkaloids against Plasmodium falciparum. Basco L.K. et al. Antimicrob Agents Chemother. 1994, 38, 1169.
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