Tilmicosin

Tilmicosin

$126.00 - 25 mg

$441.00 - 100 mg

All prices in Australian dollars

Code
BIA-T1323
Synonyms
20-Deoxy-20-(3,5-dimethylpiperidin-1-yl)-desmycosin, EL-870
CAS #
108050-54-0
Molecular Formula
C46H80N2O13
Molecular Weight
869.2
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.
Clear

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Application Notes

Tilmicosin is a semi-synthetic antibiotic derived from desmycosin (tylosin B), a minor co-metabolite of tylosin. Tilmicosin is produced by reductive amination of desmycosin. Desmycosin itself is prepared by the partial hydrolysis of tylosin with the loss of the mycarosyl sugar. The piperidinyl group at C20 of tilmicosin provides a wider spectrum of antibiotic action, in particular good protection against Pasteurella in livestock.

References

  • Synthesis and antimicrobial evaluation of 20-deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin (Tilmicosin, EL-870) and related cyclic amino derivatives. Debono M. et al., J. Antibiot. 1989, 42, 1253.

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