L-681217

L-681217

$345.00 - 0.50 mg

$1,210.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-L1044
Synonyms
L 681217
CAS #
93522-10-2
Molecular Formula
C36H53NO10
Molecular Weight
659.8
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

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Application Notes

L-681,217 is a glycolipid-type antibiotic related to the efrotomycin class, isolated from a Streptomyces sp. L 681,217 shows broad spectrum antibiotic activity against Gram positive and Gram negative bacteria. L-681,217 inhibits bacterial protein synthesis at the elongation stage, its target being elongation factor Tu (EF-Tu).

References

  • Effects of elfamycins on elongation factor Tu from Escherichia coli and Staphylococcus aureus. Hall C.C. et al., Antimicrob. Agents Chemother. 1989, 33, 322.
  • L-681,217, a new and novel member of the efrotomycin family of antibiotics. Kempf A.J. et al., J. Antibiot, 1986, 39, 1361.

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