Stachybotrylactam

Stachybotrylactam

$295.00 - 0.50 mg

$1,035.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-S1085
Synonyms
2-deoxy F1839A
CAS #
163391-76-2
Molecular Formula
C23H31NO4
Molecular Weight
385.5
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Application Notes

Stachybotrylactam is an unusual spirodihydrobenzofuranlactam mycotoxin isolated from a Stachybotrys sp. that has immunosuppressant and weak HIV protease activity. Members of this structural class show diverse activity including antiviral, endothelin and pancreatic cholesterase inhibition.

References

  • Total synthesis and structure revision of Stachybotrys spirolactams. Deng W.P. et al., J. Org. Chem. 2003, 68, 7422.
  • Novel spirodihydrobenzofuranlactams as antagonists of endothelin and as inhibitors of HIV-1 protease produced by Stachybotrys sp. I. Fermentation, isolation and biological activity. Roggo B.E. et al., J. Antibiot. 1996, 49, 13.
  • Stachybotrys toxins I, Jarvis B.B. et al., Nat. Toxins 1995, 3, 10.

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