Stachybotrylactam
Stachybotrylactam
$295.00 - 0.50 mg
$1,035.00 - 2.50 mg
All prices in Australian dollars
- Code
- BIA-S1085
- Synonyms
- 2-deoxy F1839A
- CAS #
- 163391-76-2
- Molecular Formula
- C23H31NO4
- Molecular Weight
- 385.5
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Application Notes
Stachybotrylactam is an unusual spirodihydrobenzofuranlactam mycotoxin isolated from a Stachybotrys sp. that has immunosuppressant and weak HIV protease activity. Members of this structural class show diverse activity including antiviral, endothelin and pancreatic cholesterase inhibition.
References
- Total synthesis and structure revision of Stachybotrys spirolactams. Deng W.P. et al., J. Org. Chem. 2003, 68, 7422.
- Novel spirodihydrobenzofuranlactams as antagonists of endothelin and as inhibitors of HIV-1 protease produced by Stachybotrys sp. I. Fermentation, isolation and biological activity. Roggo B.E. et al., J. Antibiot. 1996, 49, 13.
- Stachybotrys toxins I, Jarvis B.B. et al., Nat. Toxins 1995, 3, 10.