$189.00 - 0.50 mg
$662.00 - 2.50 mg
All prices in Australian dollars
- Sclertiolamine, Sclerotioriamine
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO.
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Sclerotioramine is an azaphilone pigment prepared synthetically from sclerotiorin and reported by Whalley and co-workers at the University of Liverpool in 1957. Subsequently, sclerotioramine was isolated as a natural product from various Penicillium species. Sclerotioramine is active against Gram positive bacteria, producing modest zones of inhibition against Staphylococcus epidermidis in a disk diffusion assay at a concentration of 30 μg/6 mm paper disk. Sclerotioramine inhibited Candida albicans, C. parapsilosis, C. tropicalis, and C. krusei (8, 7, 8, and 8 mm zones of inhibition, respectively). Sclerotioramine has moderate activity (IC50 16.31 μg/ml) in vitro against HepG2 cell line and has comparable activity to acarbose against α-glucosidase.
- 986. The chemistry of fungi. Part XXVIII. Sclerotiorin and its hydrogenation products. Eade R.A. et al. J Chem Soc 1957, 4913.
- Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an Atlantic forest soil-derived Penicillium citreonigrum. Wang X. et al. J Nat Prod 2020, 73, 942.
- Halogenated metabolites isolated from Penicillium citreonigrum. Yuan W-H. et al. Chem Biodiversity 2014, 11, 1078.