Sclerotigenin

Sclerotigenin

$140.00 - 1 mg

$490.00 - 5 mg

All prices in Australian dollars

Code
BIA-S1678
CAS #
65641-84-1
Molecular Formula
C16H11N3O2
Molecular Weight
277.28
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.
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Application Notes

Sclerotigenin is a benzodiazepine isolated from the sclerotia of Penicillium sclerotigenum by Gloer and co-workers at the USDA and University of Iowa, USA in 1999 as an Antiinsectan active against the caterpillar, Helicoverpa zea. Structurally, sclerotigenin forms the 7-membered diazepine by coupling two anthranilic acid moieties with glycine. Sclerotigenin is the simplest member of the fungal benzodiazepines which include asperlicins, benzomalvins and circumdatins. Sclerotigenin is an important metabolite for the chemotaxonomy of the genus Penicillium.

References

  • Sclerotigenin: a new antiinsectan benzodiazepine from the sclerotia of Penicillium sclerotigenum. Joshi B.K. et al., J. Nat. Prod. 1999, 62, 650.
  • UV-guided screening of benzodiazepine-producing species in Penicillium Larsen T.O. et al., Biochem. Syst. Ecol. 2000, 28, 881.
  • Biochemical characterization of ochratoxin A-producing strains of the genus Penicillium. Larsen T.O. et al., Appl. Environ. Microbiol. 2001, 67, 3630.

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