Sartorypyrone A

Sartorypyrone A

$209.00 - 1 mg

$732.00 - 5 mg

All prices in Australian dollars

Code
BIA-S1636
CAS #
1452396-10-9
Molecular Formula
C28H40O5
Molecular Weight
456.61
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.
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Application Notes

Sartorypyrone A is a meroterpenoid metabolite first isolated from several species of Neosartorya in Thailand. Unlike previously reported meroterpenoids, sartorypyrone B and aszonapyrone A and B which are polycyclic, sartorypyrone A has a terminal pyrone and cyclohexane separated by a nine carbon chain. Sartorypyrone A is active against Gram negative species, E. coli, and P. aeruginosa, and Gram positive S. aureus resistant strains, and inhibits biofilm formation by S. aureus and B. subtilis.

References

  • Bioactive meroditerpenes and indole alkaloids from the soil fungus Neosartorya fischeri (KUFC 6344), and the marine-derived fungi Neosartorya laciniosa (KUFC 7896) and Neosartorya tsunodae (KUFC 9213). Eamvijarn A. et al., Tetrahedron 2013, 69, 8583.
  • Antibacterial and antibiofilm activities of tryptoquivalines and meroditerpenes isolated from the marine-derived fungi Neosartorya paulistensis, N. laciniosa, N. tsunodae, and the soil fungi N. fischeri and N. siamensis. Gomes N.M. et al., Marine Drugs 2014, 12, 822.

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