Anhydroerythromycin A

Anhydroerythromycin A

$128.00 - 1 mg

$448.00 - 5 mg

All prices in Australian dollars

Synonyms
Erythromycin anhydride
CAS #
23893-13-2
Molecular Formula
C37H65NO12
Molecular Weight
715.9
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
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Application Notes

Anhydroerythromycin A is a degradation product of erythromycin formed by a complex internal rearrangement of erythromycin A on exposure to acidic conditions. In acid, erythromycin A forms the enol ether and then undergoes a second internal cyclisation of the C12–OH and C9 enol to afford the ketal, anhydroerythromycin A. Anhydroerythromycin A is an important analytical standard for erythromycin A stability studies.

References

  • Acid degradation of erythromycin A and erythromycin. Kurath B.P. et al., Experientia 1971, 27, 362.
  • Erythromycin. X. l Structure of erythromycin. Wiley P.F. J. Am. Chem. Soc. 1957, 79, 6062.

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