Rugulosin – form

Rugulosin – form

$280.00 - 1 mg

$980.00 - 5 mg

All prices in Australian dollars

Code
BIA-R1452
Synonyms
Radicalisin
CAS #
21884-45-7
Molecular Formula
C30H22O10
Molecular Weight
542.5
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

Download Data Sheets

Product Data Sheet

Application Notes

(-)-Rugulosin is the less common optical isomer of the mycotoxin, (+)-rugulosin, which was first isolated from Myrothecium verrucaria in 1968. The isomers appear not to be co-produced but both occur widely in several fungal genera. (-)-Rugulosin has been shown to be antiviral. (-)Rugulosin is the less studied of the isomers and its role as a mycotoxin is implied rather than established. There are few comparative studies of the relative potency of the isomers.

References

  • Fungal metabolites. XXXII. Renewed investigation on (-)-flavoskyrin and its analogs Takeda N. et al., Tetrahedron 1973, 29, 3703.
  • Further studies on the structures of luteoskyrin, rubroskyrin and rugulosin. Sankawa U. et al., Tet. Lett. 1968, 53, 5557.
  • Inhibition of phage growth by an antibiotic rugulosin isolated from Myrothecium verucaria. I. Properties of the anti-phage effect. Nakamura S. et al., Jpn. J. Microbiol. 1971, 5, 113.

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