Rugulosin – form
Rugulosin – form
$280.00 - 1 mg
$980.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-R1452
- Synonyms
- Radicalisin
- CAS #
- 21884-45-7
- Molecular Formula
- C30H22O10
- Molecular Weight
- 542.5
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
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Application Notes
(-)-Rugulosin is the less common optical isomer of the mycotoxin, (+)-rugulosin, which was first isolated from Myrothecium verrucaria in 1968. The isomers appear not to be co-produced but both occur widely in several fungal genera. (-)-Rugulosin has been shown to be antiviral. (-)Rugulosin is the less studied of the isomers and its role as a mycotoxin is implied rather than established. There are few comparative studies of the relative potency of the isomers.
References
- Fungal metabolites. XXXII. Renewed investigation on (-)-flavoskyrin and its analogs Takeda N. et al., Tetrahedron 1973, 29, 3703.
- Further studies on the structures of luteoskyrin, rubroskyrin and rugulosin. Sankawa U. et al., Tet. Lett. 1968, 53, 5557.
- Inhibition of phage growth by an antibiotic rugulosin isolated from Myrothecium verucaria. I. Properties of the anti-phage effect. Nakamura S. et al., Jpn. J. Microbiol. 1971, 5, 113.