Ristocetin A sulfate
Ristocetin A sulfate
$325.00 - 10 mg
$1,140.00 - 50 mg
All prices in Australian dollars
- Code
- BIA-R1113
- Synonyms
- Ristocetin, Ristomycin III, Spontin, Riston
- CAS #
- 11140-99-1
- Molecular Formula
- C95H112N8O48S
- Molecular Weight
- 2166
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.
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Application Notes
Ristocetin A sulfate is a potent antibacterial glycopeptide antibiotic that was withdrawn from clinical use following a high incidence of thrombocytopenia. Further investigation found that ristocetin A induced platelet aggregation by binding to a factor absent in people suffering from von Willebrand's disease, leading to the use of ristocetin A as an important diagnostic aid.
References
- Ristocetin A and B, two new antibiotics. Isolation and properties. Philip J.E. et al., Antibiot. Annu. 1955, 699.
- Ristocetin - a new tool in the investigation of platelet aggregation. Howard M.A. et al., Throm. Diath. Haemorrh. 1971, 26, 362.