Psychotridine

Psychotridine

$255.00 - 1 mg

$895.00 - 5 mg

All prices in Australian dollars

Code
BIA-P1960
CAS #
52617-25-1
Molecular Formula
C55H62N10
Molecular Weight
863.15
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Product Data Sheet

Application Notes

Psychotridine is the main component of an alkaloid complex isolated from Psychotria beccaroides by Lamberton and colleagues at CSIRO, Australia in 1974. Psychotridine is structurally related to hodgkinsine. The structure of psychotridine was revised in 1999. Psychotridine is cytotoxic and inhibits platelet aggregation. Psychotridine exhibits dose-dependent analgesic activity in capsaicin-induced pain models and inhibits radioligand binding postulated to involve NMDA receptors.

References

  • Psychotridine, a C55H62N10 alkaloid from Psychotria beccarioides (Rubaceae). Hart N.K. et al. Aust J Chem. 1974, 27, 639.
  • Pyrrolidinoindoline alkaloids from Psychotria oleoides and Psychotria lyciiflora. Jannic V. et al. J Nat Prod. 1999, 62, 838.
  • Cytotoxic activity of polyindoline alkaloids of Psychotria forsteriana (Rubiaceae). Roth A. et al. Plata Med. 1986, 6, 450.
  • Polyindolinic alkaloids from Psychotria forsteriana. Potent inhibitors of the aggregation of human platelets. Beretz A. et al. Planta Med. 1985, 4, 300.
  • Involvement of NMDA receptors in the analgesic properties of psychotridine.  Amador T.A. et al. Phytomed. 2001, 8, 202.

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