$204.00 - 0.50 mg
$714.00 - 2.50 mg
All prices in Australian dollars
- SF 2370
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Download Data Sheets
K252A is a staurosporine analogue isolated from a Nocardiopsis strain as a potent inhibitor of protein kinase C. K252A exhibits potent antitumor activity but shows no antimicrobial activity in vitro, or in vivo toxicity in rodents. While K252A is a potent inhibitor of Ca2+/calmodulin kinase II, it is also active against other kinases, notably myosin light chain kinase, cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and cGMP-dependent protein kinase (PKG).
- K-252a, a potent inhibitor of protein kinase C from microbial origin. Kase H. et al., J. Antibiot. 1986, 39, 1059.
- The structures of the novel protein kinase C inhibitors K-252a, b, c and d. Yasuzawa T. et al., J. Antibiot. 1986, 39, 1072.