Phanerosporic acid is the major metabolite isolated from the white wood rot fungus, Phanerochaete chrysosporium, reported by Arnone and co-workers in 1989. Phanerosporic acid is a hydrophobic orsellinic acid with a 14’-hydroxypentadecyl chain replacing the methyl 6-methyl moiety. Phanerosporic acid has broad Gram positive and Gram negative antibiotic activity, and stimulates root elongation of Lepidium sativum (garden cress). Phanerosporic acid has pronounced activity against Helicobacter pylori.
- Secondary mold metabolites. Part 27. Phanerosporic acid, a β-resorcylate obtained from Phanerochaete chrysosporium. Arnone A. et al., Phytochem. 1989, 28, 2803.
- Secondary mold metabolites. Part 28. Spirolaxine and sporotricale: two long-chain phthalides produced by Sporotrichum laxum. Arnone A. et al., Phytochem. 1990, 29, 613.
- Three new resorcylic acid derivatives from Sporotrichum laxum. Wang S. et al., Bioorg. & Med. Chem. Lett. 23, 2013, 5806.