Hydroxyoligomycin A, 21-
Hydroxyoligomycin A, 21-
$300.00 - 1 mg
$1,050.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-O1062
- Synonyms
- Nemadectin omega, LL-F28249 omega
- CAS #
- 102042-09-1
- Molecular Formula
- C45H74O12
- Molecular Weight
- 807.1
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Application Notes
21-Hydroxyoligomycin A is a rare member of the oligomycin class isolated as a co-metabolite of nemadectin, hence its original naming as nemadectin omega. Only limited literature references to this metabolite are available. However, in-house testing suggests that 21-hydroxyoligomycin has a more selective action against mammalian tumor cell lines than oligomycin A, exhibiting only weak antifungal and nematocidal activity.
References
- Structure and Absolute Stereochemistry of 21-Hydroxyoligomycin A. Wagenaar M.M. et al., J Nat Prod. 2007, in press.
- Plasmid effects on secondary metabolite production by a streptomycete synthesizing an anthelmintic macrolide.Thomas D.I. et al., J Gen Microbiol. 1991, 137, 2331.