Hydroxyoligomycin A, 21-

Hydroxyoligomycin A, 21-

$287.00 - 1 mg

$1,005.00 - 5 mg

All prices in Australian dollars

Code
BIA-O1062
Synonyms
Nemadectin omega, LL-F28249 omega
CAS #
102042-09-1
Molecular Formula
C45H74O12
Molecular Weight
807.1
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Clear

Download Data Sheets

Application Notes

21-Hydroxyoligomycin A is a rare member of the oligomycin class isolated as a co-metabolite of nemadectin, hence its original naming as nemadectin omega. Only limited literature references to this metabolite are available. However, in-house testing suggests that 21-hydroxyoligomycin has a more selective action against mammalian tumor cell lines than oligomycin A, exhibiting only weak antifungal and nematocidal activity.

References

  • Structure and Absolute Stereochemistry of 21-Hydroxyoligomycin A. Wagenaar M.M. et al., J Nat Prod. 2007, in press.
  • Plasmid effects on secondary metabolite production by a streptomycete synthesizing an anthelmintic macrolide.Thomas D.I. et al., J Gen Microbiol. 1991, 137, 2331.

Other Products