Helminthosporol

Helminthosporol

$260.00 - 1 mg

$910.00 - 5 mg

All prices in Australian dollars

Code
BIA-H2839
CAS #
1619-29-0
Molecular Formula
C15H24O2
Molecular Weight
236.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Helminthosporol is a rare sesquiterpene isolated from Helminthosporium, Bipolaris and other fungal species. Helminthosporol demonstrates phytotoxic effects in some plant models, affecting membrane permeability, inhibiting mitochondrial oxidative phosphorylation, photophosphorylation in chloroplasts, proton pumping across the cell plasma membrane, and 1,3-β-glucan synthase activity. Helminthosporol also demonstrates modest giberellin-like activity, inducing seed germination. Helminthosporol reversibly inhibits ACAT in rat liver microsomes at a concentration of 0.5 mM.

References

  • Isolation of helminthosporol as a natural plant growth regulator and its chemical structure. Tamura S. et al. Agric Biol Chem. 1963, 27, 738.
  • Bioactive sesquiterpenes from an endophytic fungus Bipolaris sorokiniana isolated from a popular medicinal plant Costus speciosus. Qader M.M. et al. Mycology 2017, 8, 17.
  • Plant cell membranes as biochemical targets of the phytotoxin helminthosporol. Briquet M. et al. J Bioenergetics Biomembranes 1998, 30, 285.
  • Helminthosporic acid functions as an agonist for gibberellin receptor. Miyazaki S. et al. Biosci Biotechnol Biochem. 2017, 81, 2152.
  • Inhibition of acyl:Co-A cholesterol transferase by helminthosporol and its related compounds. Park J.K. et al. J Antibiot. 1993, 46, 1303.

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