Embelin

Embelin

$100.00 - 0.10 mg

$350.00 - 0.50 mg

All prices in Australian dollars

Code
BIA-E2354
Synonyms
Embelic acid, Emberine, NSC 91874
CAS #
550-24-3
Molecular Formula
C17H26O4
Molecular Weight
294.39
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO

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Product Data Sheet

Application Notes

Embelin is benzoquinone metabolite isolated from Embelia ribes first reported in 1931. Embelin has a broad bioprofile, including antioxidant, anti-inflammatory, antitumor, antibacterial, antiviral, antidiabetic and anti-estrogenic activities. Embelin inhibits cell proliferation, induces G1 arrest and triggers apoptosis in CRPC cells, possibly via the Akt​/NF-​κB​/survivin signaling pathway. Embelin is a privileged structure for the synthesis of antibacterial compounds.

References

  • CCLXXXVIII.—The constitution and synthesis of embelic acid (embelin), the active principle of Embelia Ribes. Hasan K.H. & Stedman E. J Chem Soc. 1931.
  • Antioxidant properties of embelin in cell culture: Electrochemistry and theoretical mechanism of scavenging. Potential scavenging of superoxide radical through the membrane cell. Caruso F. et al. Antioxidants 2020, 9, 382.
  • Inhibition of Akt​/NF-​κB​/survivin pathway by embelin on castration-​resistant prostate cancer cells Xu T. et al. Int J Clin Exp Med. 2017, 10, 4386.

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