Dehydrocurvularin, 10,11-

Dehydrocurvularin, 10,11-

$300.00 - 1 mg

$1,050.00 - 5 mg

All prices in Australian dollars

Code
BIA-D1399
CAS #
1095588-70-7
Molecular Formula
C16H18O5
Molecular Weight
290.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

Download Data Sheets

Product Data Sheet

Application Notes

Dehydrocurvularin is a 12-membered macrocyclic lactone incorporating a resorcinyl moiety, produced by a number of fungal species including Curvularia, Penicillium and Alternaria. Dehydrocurvularin inhibits cell division by disrupting mitotic spindle formation and acts as a developmental regulator by inhibiting self-sporulation in Alternaria alternata. More recently dehydrocurvularin has been shown to have antimalarial activity.

References

  • Curvularin. Part V. The compound C16H18O5, α,β-dehydrocurvularin. Munro H.D. et al., J. Chem. Soc. 1967, 947.
  • Isolation of alpha, beta-dehydrocurvularin and, beta-hydroxycurvularin from Alternaria tomato as sporulation suppressing factors. Hyeon S-B. et al., Agri. Biol. Chem. 1976, 44, 1663.
  • Betagamma-dehydrocurvularin and related compounds as nematocides of Pratylenchus penetrans from the fungus Aspergillus sp. Kusano M. et al., Biosci. Biotechnol. Biochem. 2003, 67, 1413.

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