Cytochalasin C

Cytochalasin C

$150.00 - 1 mg

$525.00 - 5 mg

All prices in Australian dollars

Code
BIA-C1169
CAS #
22144-76-9
Molecular Formula
C30H37NO6
Molecular Weight
507.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

Download Data Sheets

Product Data Sheet

Application Notes

Cytochalasin C is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic changes in animals and plants. The cytochalasins act by disrupting actin microfilaments and these effects are most noticeable by the inhibition of cell division.

References

  • Actin assembly activity of cytochalasins and cytochalasin analogs assayed using fluorescence photobleaching recovery. Walling E. A. et al., Arch. Biochem. Biophys. 1988, 264, 321.
  • Alteration in cell morphology triggers transforming growth factor-beta 1, collagenase, and tissue inhibitor of metalloproteinases-I expression in normal and hypertrophic scar fibroblasts. Varedi M. et al., ; J. Invest. Dermatol. 1995, 104, 118.

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