$63.00 - 1 mg
$221.00 - 5 mg
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- 7(S)-Chloro-7-deoxylincomycin 2-phosphate, Cleocin phosphate, Clindamycin phosphate, NSC 618653, U 28508
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.
Download Data Sheets
Clindamycin 2-phosphate is a salt of clindamycin, a semi-synthetic lincosamide. The salt is prepared by selective phosphorylation of the 2-hydroxy moiety of the sugar of clindamycin. The introduction of the phosphate affords improved solubility for injectable formulations. Like other members of the lincosamide family, clindamycin 2-phosphate is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis.
- Chemical modification of lincomycin. Magerlein B.J. et al., Antimicrob. Agents Chemother. 1966, 6, 727.
- Synthesis and bioactivity of lincomycin-2-phosphate. Morozowich W.J. Pharm. Sci. 1969, 58, 1485.