Butyrolactone V
Application Notes
Butyrolactone V is a saturated dibenzylbutyrolactone lignan isolated from a strain of Aspergillus by Lin and collaborators, Xiamen University, China in 2009. Butyrolactone V is moderately active against the parasites, Plasmodium falciparum, Leishmania amazonensis and Schistosoma mansoni. Butyrolactone V is a DPPH radical scavenger and is cytotoxic to selected breast tumor cell lines with low toxicity to normal human fibroblasts.
References
- Secondary metabolites of Aspergillus sp. F1, a commensal fungal strain of Trewia nudiflora. Lin T. et al., Nat. Prod. Res. 2009, 23, 77.
- Butyrolactones from the fungus Aspergillus terreus BCC 4651. Haritakun R. et al., Chem. Pharm. Bull. 2010, 58, 1545.
- Bioactive compounds of Aspergillus terreus-F7, an endophytic fungus from Hyptis suaveolens (L.) Poit. Da Silva I.P. et al., World J. Microbiol. Biotechnol. 2017, 33, 62.