Butyrolactone V

Butyrolactone V

$255.00 - 1 mg

$895.00 - 5 mg

All prices in Australian dollars

Code
BIA-B1826
CAS #
1151509-01-1
Molecular Formula
C24H24O8
Molecular Weight
440.44
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

Butyrolactone V is a saturated dibenzylbutyrolactone lignan isolated from a strain of Aspergillus by Lin and collaborators, Xiamen University, China in 2009. Butyrolactone V is moderately active against the parasites, Plasmodium falciparum, Leishmania amazonensis and Schistosoma mansoni. Butyrolactone V is a DPPH radical scavenger and is cytotoxic to selected breast tumor cell lines with low toxicity to normal human fibroblasts.

References

  • Secondary metabolites of Aspergillus sp. F1, a commensal fungal strain of Trewia nudiflora. Lin T. et al., Nat. Prod. Res. 2009, 23, 77.
  • Butyrolactones from the fungus Aspergillus terreus BCC 4651. Haritakun R. et al., Chem. Pharm. Bull. 2010, 58, 1545.
  • Bioactive compounds of Aspergillus terreus-F7, an endophytic fungus from Hyptis suaveolens (L.) Poit. Da Silva I.P. et al., World J. Microbiol. Biotechnol. 2017, 33, 62.

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