Beauvericin

Beauvericin

$183.00 - 5 mg

$641.00 - 25 mg

All prices in Australian dollars

Code
BIA-B1238
CAS #
26048-05-5
Molecular Formula
C45H57N3O9
Molecular Weight
784
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Clear

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Application Notes

Beauvericin is a cyclic depsipeptide isolated from several fungal genera, notably Beauveria and Fusarium, first reported in 1969. Beauvericin exhibits broad antifungal, antibacterial, antiprotozoan and insecticidal activities. At the molecular level, beauvericin exhibits ionophore properties, and inhibits acyl-CoA:cholesterol acyltransferase activity. Beauvericin induces apoptosis by elevating intracellular calcium levels.

References

  • The structure of beauvericin, a new depsipeptide antibiotic toxic to Artemia salina. Hamill Z. R. L. et al., Tet. Letters 1969, 4255.
  • Inhibition of acyl-CoA:cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. Tomoda H. et al., J. Antibiot. 1992, 45, 1626.
  • Beauvericin Production by Fusarium Species. Logrieco A. et al., Appl. Environ. Microbiol. 1998, 64, 3084.

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