Auroglaucin, first reported in 1937 by Raistrick and co-workers, is a yellow pigment produced by Aspergillus glaucus. Auroglaucin is potently active against Plasmodium falciparum (IC50 1-2 µg/mL) and Leishmania. Auroglaucin inhibits Candida glabrata and C. krusei with IC50 OF 7.33 and 10.93 µg/mL. Auroglaucin has high binding affinity for human opioid or cannabinoid receptors and demonstrates antioxidant activity.
- The chemistry of Aspergillus colouring matters. Part I. Raistrick H. et al. J Chem Soc 1937, 80.
- Antimicrobial and antiprotozoal activities of secondary metabolites from the fungus Eurotium repens. Gao J. et al. Med Chem Res 2012, 21, 3080.
- Antioxidants produced by Eurotium herbariorum of filamentous fungi used for the manufacture of karebushi, dried bonito (Katsuobushi). Miyake Y. et al. Biosci Biotech Biochem 2009, 73, 1323.