Aselacin C

Aselacin C

$166.00 - 0.10 mg

$581.00 - 0.50 mg

All prices in Australian dollars

Code
BIA-A2541
CAS #
156223-08-4
Molecular Formula
C46H66N8O11
Molecular Weight
907.06
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol or DMSO
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Application Notes

Aselacin C is a cyclic pentadepsipeptide isolated from an Acremonium species in 1994 by researchers at Abbott Laboratories. Aselacin C inhibits binding of endothelin to its receptor in bovine atrial and procine cerebral membranes with an IC50 of approximately 20 µ/mL.

References

  • Aselacins, novel compounds that inhibit binding of endothelin to its receptor. I. The producing organism, fermentation and biological activity. Jackson M. et al. J Antibiot 1994, 47, 523.
  • Aselacins, novel compounds that inhibit binding of endothelin to its receptor. II. Isolation and elucidation of structures. Hochlowski J.E. et al. J Antibiot 1994, 47, 528.

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