Aselacin C
Aselacin C
$190.00 - 0.1 mg
$665.00 - 0.5 mg
All prices in Australian dollars
- Code
- BIA-A2541
- Synonyms
- -
- CAS #
- 156223-08-4
- Molecular Formula
- C46H66N8O11
- Molecular Weight
- 907.1
- Purity
- >95% by HPLC
- Long Term Storage
- -20ยฐC
- Solubility
- Soluble in methanol or DMSO.
Download Data Sheets
Application Notes
Aselacin C is a cyclic pentadepsipeptide isolated from an Acremonium species in 1994 by researchers at Abbott Laboratories. Aselacin C inhibits binding of endothelin to its receptor in bovine atrial and procine cerebral membranes with an IC50 of approximately 20 ยต/mL.
References
- Aselacins, novel compounds that inhibit binding of endothelin to its receptor. I. The producing organism, fermentation and biological activity. Jackson M. et al. J Antibiot 1994, 47, 523.
- Aselacins, novel compounds that inhibit binding of endothelin to its receptor. II. Isolation and elucidation of structures. Hochlowski J.E. et al. J Antibiot 1994, 47, 528.
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