Xanthopterin

Xanthopterin

$75.00 - 1 mg

$265.00 - 5 mg

All prices in Australian dollars

Code
BIA-X2595
Synonyms
2-Aminopteridine-4,6-diol, 6-Hydroxy-2-amino-4-hydroxypteridine, NSC 41836, NSC 91557
CAS #
119-44-8
Molecular Formula
C6H5N5O2
Molecular Weight
179.14
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in methanol with 0.3% v/v ammonia

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Product Data Sheet

Application Notes

Xanthopterin is a polar yellow pigment that has long been known as a metabolite of wasps and butterflies. Xanthopterin inhibits proliferation of primary renal proximal tubule and LLC-PK cells while in a growth phase and malignant human prostate PC-3 cells in a concentration and time dependent manner. Differential effects on cell growth were seen dependent upon the cell origin and their state of proliferation. Xanthopterin is a biomarker for human liver disease. Xanthopterin is poorly soluble in most solvents.

References

  • Uber das vorkommen der pterin in wespen und schmetterlungen und uber einige neue beobachtungen am leukopterin und xanthopterin. Schopf. C. et al. Justus Liebigs Ann Chem. 1933, 507, 266.
  • Differential effect of xanthopterin and biopterin on cell growth. Rubenstein M. et al. Int J Biochem. 1993, 25, 1873.
  • A comparative study of urinary xanthopterin and neopterin in liver diseases. Fukuda A. et al. Eur J Clin Chem Clin Biochem. 1993, 31, 129.

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