Violacein

Violacein

$326.00 - 1 mg

$1,139.00 - 5 mg

All prices in Australian dollars

Code
BIA-V1327
Synonyms
Anorosin
CAS #
548-54-9
Molecular Formula
C20H13N3O3
Molecular Weight
343.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Clear

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Application Notes

Violacein is an intense violet pigment formed by the condensation of two tryptophan units, found in a number of bacteria, notably Chromobacterium violaceum. The regulation of pigment biosynthesis is the chromogenic basis for the use of C. violaceum CV26 for the detection of quorum sensing mediators. Violacein exhibits broad spectrum activity against bacteria, protozoans (including malaria), viruses and mammalian cell lines. Violacein cell toxicity resembles TNF-α signal transduction.

References

  • The chemistry of bacteria. Part II. Some degradation products of violacein. Beer R.J.S. et al., J. Chem Soc. 1949, 885.
  • Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acyl homoserine lactones. McClean K.H. et al., Microbiol. 1997, 143, 3703.
  • Molecular mechanism of violacein-mediated human leukemia cell death. Ferreira C.V. et al., Blood 2004, 104, 1459.

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