Tulathromycin

Tulathromycin

$100.00 - 5 mg

$350.00 - 25 mg

All prices in Australian dollars

Code
BIA-T1370
Synonyms
Tulathromycin A
CAS #
217500-96-4
Molecular Formula
C41H79N3O12
Molecular Weight
806.1
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.
Clear

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Application Notes

Tulathromycin is a semi-synthetic erythromycin belonging to the ring expanded aza–erythromycins. Ring expansion improves the acid lability compared with the parent erythromycins. Tulathromycin is regarded as the first of the triamilides, having a third amino (propylaminomethylene) group on a sugar to improve absorption. This modification provides a mixture of the two tulathromycin isomers (90:10) present in the commercial animal health product.

References

  • Synthesis and activity of a novel class of tribasic macrocyclic antibiotics: The triamilides. Letavic M.A. et al., Bioorg. Med. Chem. Lett. 2002, 12, 2771.
  • An analytical method for the analysis of tulathromycin, an equilibrating triamilide, in bovine and porcine plasma and lung. Gáler D. et al., J. Agric. Food Chem. 2004, 52, 2179.
  • Tulathromycin: An overview of a new triamilide antimicrobial for livestock respiratory disease. Evans N.A. Vet. Therapeutics 2005, 6, 83.

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