Tryptoquivaline D
Application Notes
Tryptoquivaline D (nortryptoquivaline, fumitremorgin D) is a tremorgenic mycotoxin isolated from Aspergillus fumigatus and A. clavatus. The biological profile of tryptoquivaline D is largely unexplored, however other members of the fumitremorgin family have antitumor and insect antifeedant activity and are active against phytopathogenic fungi.
References
- Four new mycotoxins of Aspergillus clavatus related to tryptoquivaline. Bucchi G. et al. J Org Chem. 1977, 42, 244.
- Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. I. Taxonomy, fermentation, isolation and biological properties. Cui C.B. et al., J. Antibiot. 1996, 49, 527.
- Metabolites from Aspergillus fumigatus, an endophytic fungus associated with Melia azedarach, and their antifungal, antifeedant, and toxic activities. Li X-J. J Ag Food Chem 2012, 60, 3424.