Sulochrin
Sulochrin
$225.00 - 1 mg
$790.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-S1089
- CAS #
- 519-57-3
- Molecular Formula
- C17H16O7
- Molecular Weight
- 332.3
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Download Data Sheets
Application Notes
Sulochrin is a fungal metabolite isolated from a number of Aspergillus and Penicillium sp. An anti-angiogenic agent, sulochrin inhibits VEGF leading to inhibition of capillary-like tube formation of human umbilical vein endothelial cells. Sulochrin also inhibits eosinophil activation and chemotaxis.
References
- Fungal metabolites, asterric acid derivatives inhibit vascular endothelial growth factor (VEGF)-induced tube formation of HUVECs. Lee H.J. et al., J. Antibiot. 2002, 55, 552.
- Effects of ortho-substituent groups of sulochrin on inhibitory activity to eosinophil degranulation. Ohashi H. et al., Bioorg. Med. Chem. Lett. 1999, 9, 1945.
- Sulochrin inhibits eosinophil activation and chemotaxis. Ohashi H. et al., Inflamm. Res. 1998, 47, 409.
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