Remisporine B is a metabolite of a marine fungus Remispora maritima. Remisporine B is a unique cyclopentachromone dimer resulting from a spontaneous Diels-Alder reaction of remisporine A, reported by resaerchers at Wyeth Research in 2003. Remisporine B is a weak antitumor active with IC50 of 83.1 μg/mL for K562 and 75.3 μg/mL for HL-60 tumor cell lines.
- Remisporine B, a novel dimeric chromenone derived from spontaneous Diels–Alder reaction of remisporine A. Kong F. & Carter G.T. Tetrahedron Lett. 2003, 44, 3119.
- Rare chromones from a fungal mutant of the marine-derived Penicillium purpurogenum G59. Xia M-W. et al. Mar. Drugs 2015, 13, 5219.