Quinolactacin A1

Quinolactacin A1

$360.00 - 1 mg

$1,260.00 - 5 mg

All prices in Australian dollars

Code
BIA-Q1073
CAS #
815576-68-2
Molecular Formula
C16H18N2O2
Molecular Weight
270.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Product Data Sheet

Application Notes

Quinolactacin A1 is the dominant analogue of a family of quinolone metabolites produced by Penicillium citrinum. Quinolactacin A1 rapidly epimerises to equilibrate with its diastereomer quinolactacin A2 in protic solvents. The mixture has been shown to inhibit acetylcholinesterase and TNF production.

References

  • Biosynthesis of quinolactacin A, a TNF production inhibitor. Sasaki T. et al., J Antibiot. 2006, 59, 418.
  • Quinolactacins A1 and A2, new acetylcholinesterase inhibitors from Penicillium citrinum. Kim W.G. et al., J Antibiot. 2001, 54, 831.
  • Quinolactacins A, B and C: novel quinolone compounds from Penicillium sp. EPF-6. I. Taxonomy, production, isolation and biological properties. Kakinuma N. et al., J Antibiot. 2000, 53,1247.

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