Quinaldopeptin
Quinaldopeptin
$365.00 - 0.50 mg
$1,280.00 - 2.50 mg
All prices in Australian dollars
- Code
- BIA-Q1072
- Synonyms
- BMY 28662, BU 3845T
- CAS #
- 130743-07-6
- Molecular Formula
- C62H78N14O14
- Molecular Weight
- 1243.4
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor water solubility.
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Application Notes
Quinaldopeptin is a symmetrical, cyclic decapeptide from an Amycolatopsis sp. that is a bis-intercalator of DNA, exhibiting strong in vitro antimicrobial and cytotoxic activity. Quinaldopeptin significantly prolongs the survival time of mice inoculated with a murine tumor, and also shows weak nematocidal activity. Quinaldopeptin is related to the luzopeptins and sandramycin.
References
- Quinaldopeptin, a novel antibiotic of the quinomycin family. Toda S. et al., J. Antibiot. 1990, 43, 796.
- Structure of actinotetraose hexatiglate, a unique glucotetraose from an actinomycete bacterium. Rickards R.W. et al., J. Antibiot. 1998, 51, 1093.