Quinaldopeptin

Quinaldopeptin

$365.00 - 0.50 mg

$1,280.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-Q1072
Synonyms
BMY 28662, BU 3845T
CAS #
130743-07-6
Molecular Formula
C62H78N14O14
Molecular Weight
1243.4
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor water solubility.

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Application Notes

Quinaldopeptin is a symmetrical, cyclic decapeptide from an Amycolatopsis sp. that is a bis-intercalator of DNA, exhibiting strong in vitro antimicrobial and cytotoxic activity. Quinaldopeptin significantly prolongs the survival time of mice inoculated with a murine tumor, and also shows weak nematocidal activity. Quinaldopeptin is related to the luzopeptins and sandramycin.

References

  • Quinaldopeptin, a novel antibiotic of the quinomycin family. Toda S. et al., J. Antibiot. 1990, 43, 796.
  • Structure of actinotetraose hexatiglate, a unique glucotetraose from an actinomycete bacterium. Rickards R.W. et al., J. Antibiot. 1998, 51, 1093.

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