Pyrrole-2-carboxylic acid

Pyrrole-2-carboxylic acid

$60.00 - 5 mg

$210.00 - 25 mg

All prices in Australian dollars

Code
BIA-P1572
Synonyms
Mialine, Minaline, NCS 48130
CAS #
634-97-9
Molecular Formula
C5H5NO2
Molecular Weight
111
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

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Application Notes

Pyrrole-2-carboxylic acid is small amphoteric polar metabolite produced by many Streptomyces species, often co-produced with its dimer, pyrocoll. Pyrrole-2-carboxylic acid is an important dereplication standard in discovery, displaying a distinctive UV spectrum and a broad range of biological activities, albeit weak. More recently, pyrrole-2-carboxylic has demonstrated antiparasitic activity against Trypanosomes by selective proline racemase inhibition and has potent antifungal activity against Phytophthora.

References

  • Pyrocoll, an antibiotic, antiparasitic and antitumor compound produced by a novel alkaliphilic Streptomyces strain. Dietera A. et al., J Antibiot. 2003, 56, 639.

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