Protoporphyrin, disodium salt
Protoporphyrin, disodium salt
$56.00 - 25 mg
$196.00 - 100 mg
All prices in Australian dollars
- Code
- BIA-P2300
- Synonyms
- Depocolin S, Disodium protoporphyrin, Prolmon
- CAS #
- 50865-01-5
- Molecular Formula
- C34H34N4O4.Na2
- Molecular Weight
- 606.6
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in methanol or DMSO
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Application Notes
Protoporphyrin disodium is the salt of protoporphyrin, an endogenous metabolite of living organisms. Protoporphyrin is a photosensitizer. Protoporphyrin is a branch point in the biosynthetic pathway leading to haem by insertion of iron and chlorophylls by insertion of Mg and further side-chain transformation. Protoporphyrin and its derivatives are active against human immunodeficiency virus.
References
- Biosynthesis of the pigments of life: formation of the macrocycle. Battersby A.R. et al. Nature 1980, 285, 1.
- Reduced gene expression at the branch point of chlorophyll and heme biosynthesis in Arctic Chlorella ArM0029B. Vikramathithan J. et al. Plant Biotechnol Rep. 2017, 11, 9.
- In vitro studies on the protoporphyrin uptake and photosensitivity of normal skin fibroblasts and fibroblasts from patients with erythropoietic protoporphyria. Schothorst A.A. et al. J Invest Derm. 1977, 69, 551.
- Anti-HIV activity of protoporphyrin. Asanaka M. et al. AIDS 1989, 3, 403.
- Modeling of anti-HIV-1 activity of a diverse set of porphyrin derivatives. Vanyur R. et al. Magyar Kemiai Folyoirat, Kemiai Kozlemenyek 2004, 109, 71.