Pimprinine
Pimprinine
$280.00 - 1 mg
$980.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-P1070
- Synonyms
- 5-(3-Indolyl)-2-methyloxazole, WS 30581C, APHE 3
- CAS #
- 13640-26-1
- Molecular Formula
- C12H10N2O
- Molecular Weight
- 198.2
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Download Data Sheets
Application Notes
Pimprinine is an indole alkaloid produced by many species of Streptomyces. Pimprinine is a potent inhibitor of monoamine oxidase. More recently, pimprinine showed promising anticonvulsant activity in electric seizure threshold tests in mice, comparable to phenylhydantoin. Pimprinine also inhibits tremorine-induced tremors and analgesia in mice.
References
- Isolation, characterization and synthesis of pimprinine, pimprinethine and pimprinaphine, metabolites of Streptoverticillium olivoreticuli. Koyama Y. et al., Agri Biol Chem 1981, 45, 1285.
- Pimprinine, an extracellular alkaloid produced by Streptomyces CDRIL-312: fermentation, isolation and pharmacological activity. Naik S.R. et al., J Biotechnol. 2001, 88, 1.
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