Parvodicin complex

Parvodicin complex

$125.00 - 5 mg

$440.00 - 25 mg

All prices in Australian dollars

Code
BIA-P1372
Synonyms
A 40926 complex
CAS #
187888-13-7
Molecular Formula
C83H88Cl2N8O29 (for C1)
Molecular Weight
1732.5 (for C1)
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.

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Application Notes

Parvodicin complex is a family of glycopeptides with potent antibiotic activity, isolated from Actinomadura parvosata. Structurally the parvodicins share a common cyclic peptide core with ristocetin. The analogues within the complex vary in the fatty acid substitution on the aminosugar. Like other glycopeptides in this class, parvodicin complex inhibits cell wall formation by binding to D-alanine-D-alanine residues. Parvodicin complex is a precursor to the synthetic glycopepide, dalbavancin.

References

  • Parvodicin, a novel glycopeptide from a new species, Actinomadura parvosata: Discovery, taxonomy, activity and structure elucidation. Christensen S.B. et al., J. Antibiot. 1987, 40, 970.
  • Dalbavancin: a novel antimicrobial. Chen A.Y. et al., Int. J. Clin. Pract. 2007, 61, 853.

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