Parvodicin complex
Parvodicin complex
$125.00 - 5 mg
$440.00 - 25 mg
All prices in Australian dollars
- Code
- BIA-P1372
- Synonyms
- A 40926 complex
- CAS #
- 187888-13-7
- Molecular Formula
- C83H88Cl2N8O29 (for C1)
- Molecular Weight
- 1732.5 (for C1)
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.
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Application Notes
Parvodicin complex is a family of glycopeptides with potent antibiotic activity, isolated from Actinomadura parvosata. Structurally the parvodicins share a common cyclic peptide core with ristocetin. The analogues within the complex vary in the fatty acid substitution on the aminosugar. Like other glycopeptides in this class, parvodicin complex inhibits cell wall formation by binding to D-alanine-D-alanine residues. Parvodicin complex is a precursor to the synthetic glycopepide, dalbavancin.
References
- Parvodicin, a novel glycopeptide from a new species, Actinomadura parvosata: Discovery, taxonomy, activity and structure elucidation. Christensen S.B. et al., J. Antibiot. 1987, 40, 970.
- Dalbavancin: a novel antimicrobial. Chen A.Y. et al., Int. J. Clin. Pract. 2007, 61, 853.