Ophiobolin A

Ophiobolin A

$197.00 - 1 mg

$690.00 - 5 mg

All prices in Australian dollars

Synonyms
Cochliobolin A, Ophiobolin, Ophiobalin
CAS #
6/05/4611
Molecular Formula
C25H36O4
Molecular Weight
400.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Clear

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Application Notes

Ophiobolin A is the dominant member of a class of phytotoxic metabolites produced by plant pathogenic fungi. Ophiobolin A acts by inhibiting calmodulin action in calcium regulation.

References

  • Calmodulin and lipid binding to synaptobrevin regulates calcium-dependent exocytosis. Quetglas S. EMBO J. 2002, 21, 3970.
  • The biology of ophiobolins. Au T.K. et al., Life Sci. 2000, 67, 733. (Review)

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