Oligomycin D
Oligomycin D
$315.00 - 0.50 mg
$1,105.00 - 2.50 mg
All prices in Australian dollars
- Code
- BIA-O1438
- Synonyms
- Rutamycin, 26-demethyloligomycin A, A 272, RR 32705, Rutamycin A
- CAS #
- 1404-59-7
- Molecular Formula
- C44H72O11
- Molecular Weight
- 777
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Application Notes
Oligomycin D (rutamycin) is macrocyclic lactone belonging to the oligomycin class but identified from different species of Streptomyces in 1961. Like oligomycin A, oligomycin D inhibits mitochondrial F1F0-ATPase and is an important bioprobe to study the organisation of ATPase on the mitochondrial membrane. Oligomycin D exhibits a broad biological profile including antifungal, antitumor and nematocidal activities.
References
- Antifungal antibiotic rutamycin and process for the production thereof. Thompson R.Q. US Patent 3,310,468, 1967.
- Assembly of the mitochondrial system. Purification of a mitochondrial product of the ATPase. Sierra M.F. & Tzagoloff A. Proc. Natl. Acad. Sci. U.S.A. 1973, 70, 3155.