Oligomycin D

Oligomycin D

$315.00 - 0.50 mg

$1,105.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-O1438
Synonyms
Rutamycin, 26-demethyloligomycin A, A 272, RR 32705, Rutamycin A
CAS #
1404-59-7
Molecular Formula
C44H72O11
Molecular Weight
777
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Application Notes

Oligomycin D (rutamycin) is macrocyclic lactone belonging to the oligomycin class but identified from different species of Streptomyces in 1961. Like oligomycin A, oligomycin D inhibits mitochondrial F1F0-ATPase and is an important bioprobe to study the organisation of ATPase on the mitochondrial membrane. Oligomycin D exhibits a broad biological profile including antifungal, antitumor and nematocidal activities.

References

  • Antifungal antibiotic rutamycin and process for the production thereof. Thompson R.Q. US Patent 3,310,468, 1967.
  • Assembly of the mitochondrial system. Purification of a mitochondrial product of the ATPase. Sierra M.F. & Tzagoloff A. Proc. Natl. Acad. Sci. U.S.A. 1973, 70, 3155.

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