Nourseothricin sulfate

Nourseothricin sulfate

$199.00 - 1 mg

$697.00 - 5 mg

All prices in Australian dollars

Molecular Formula
Molecular Weight
>95% by HPLC
Long Term Storage
Soluble in methanol or DMSO

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Application Notes

Nourseothricin sulfate is a complex of streptothricins C, D, E and F, isolated from Streptomyces noursei. Nourseothricin is structurally unrelated to other aminoglycosides with a glucosamine bearing a carbamoyl at the 4-hydroxy position linked to an atypical amino acid, streptolidine, via a β-glycoside linkage. The members of the complex differ in the length of the peptide side chain containing 1, 2, 3 or 4 ß-lysine residues, respectively. Nourseothricin is active against many prokaryotic and selected eukaryotic species, including yeasts, fungi, protozoa, insects and plants. Nourseothricin is inactivated by acetylation of the β-amino group of the β-lysine residue, conferred by the NAT-1 gene.


  • Streptomyces antibiotics. VI. Isolation of streptothricin. Peck R.L. et al. J Am Chem Soc. 1946, 68, 772.
  • Total chemical structure of streptothricin. Kusumoto S. et al. J Antibiot. 1982, 35, 925.
  • Bacterial resistance to streptothricins. Haupt I. and Thrum H. J Basic Microbiol. 1985, 25, 335.

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