Moenomycin complex

Moenomycin complex

$215.00 - 5 mg

$755.00 - 25 mg

All prices in Australian dollars

Code
BIA-M1297
Synonyms
Bambermycin, Flavomycin
CAS #
11015-37-5
Molecular Formula
C69H107N4O35P (for A)
Molecular Weight
1583.6 (for A)
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.

Download Data Sheets

Product Data Sheet

Application Notes

Moenomycin complex is a mixture of five major components, A, A12, C1, C3 and C4, isolated from several strains of Streptomyces in the 1960s. Moenomycins are high molecular weight phosphoglycolipids with potent antibiotic activity used in animal health. Moenomycins are the only antibiotic known to selectively inhibit the transglycosylation step catalysed by penicillin-binding protein 1b.

References

  • Moenomycin, a new antibiotic. II. Characterization and chemistry. Huber G. et al., Antimicrob. Agents Chemother. 1965, 5, 737.
  • Membrane intermediates in the peptidoglycan metabolism of Escherichia coli: Possible roles of PBP 1b and PBP 3. Van Heijenoort Y. et al., J. Bacteriol. 1992, 174, 3549.

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