Mitorubrin

Mitorubrin

$250.00 - 1 mg

$875.00 - 5 mg

All prices in Australian dollars

Code
BIA-M2921
CAS #
3403-71-2
Molecular Formula
C21H18O7
Molecular Weight
382.36
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO.

Download Data Sheets

Product Data Sheet

Application Notes

Mitorubrin is an azaphilone isolated from the phytotoxic fungus, Penicillium rubrum. Mitorubrin is a weak antifungal and inhibitor of geranylgeranyl transferase. Mitorubrin and its derivatives were patented in Japan in 1996 as dihydrofolate reductase inhibitors for the treatment of protozoal diseases.

References

  • The structures of mitorubrin and mitorubrinol. Buechi G et al. J Am Chem Soc. 1965, 87, 3484.
  • New fungal metabolite geranylgeranyl transferase inhibitors with antifungal activity. Singh S.B. et al. Nat Prod Res. 2005, 19, 739.

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