$96.00 - 5 mg
$336.00 - 25 mg
All prices in Australian dollars
- Klinomycin, Minocycline chloride, Minomycin, NSC 141993
- CAS #
- Molecular Formula
- Molecular Weight
- >95% by HPLC
- Long Term Storage
- Soluble in ethanol, methanol, DMF or DMSO. Good water solubility.
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Minocycline hydrochloride is a salt prepared from minocycline, taking advantage of the two basic dimethylamino groups which protonate and readily form a salt from hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, minocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.
- The 6-deoxytetracyclines. VII. Alkylated aminotetracyclines possessing unique antibacterial activity. Martel M.J. & Boothe J.H. J. Med. Chem. 1967, 10, 44.
- Synthesis of 7-dimethylamino-6-demethyl-6-deoxytetracycline (minocycline) via 9-nitro-6-demethyl-6-deoxytetracycline. Church R.F.R. et al., J. Org. Chem. 1971, 36, 723.