Marcfortine A
Marcfortine A
$380.00 - 1 mg
$1,330.00 - 5 mg
All prices in Australian dollars
- Code
- BIA-M1103
- Synonyms
- UK 111866
- CAS #
- 75731-43-0
- Molecular Formula
- C28H35N3O4
- Molecular Weight
- 477.6
- Purity
- >95% by HPLC
- Long Term Storage
- -20°C
- Solubility
- Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
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Application Notes
Marcfortine A is an indole alkaloid, isolated from Aspergillus and Pencillium species, with potent nematocidal activity. The marcfortines are structurally related to paraherquamides and are thought to act by blocking cholinergic neuromuscular transmission.
References
- Further novel metabolites of the paraherquamide family. Blanchflower S.E. et al., J. Antibiot. 1993, 46, 1355.
- Anthelmintic paraherquamides are cholinergic antagonists in gastrointestinal nematodes and mammals. Zinser E.W. et al., J. Vet. Pharmacol. Ther. 2002, 25, 241.
- Aspergillicins A-E: five novel depsipeptides from the marine-derived fungus Aspergillus carneus. Capon R.J. et al., Org. Biomol. Chem. 2003, 1, 1856.