Marcfortine A

Marcfortine A

$380.00 - 1 mg

$1,330.00 - 5 mg

All prices in Australian dollars

Code
BIA-M1103
Synonyms
UK 111866
CAS #
75731-43-0
Molecular Formula
C28H35N3O4
Molecular Weight
477.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Application Notes

Marcfortine A is an indole alkaloid, isolated from Aspergillus and Pencillium species, with potent nematocidal activity. The marcfortines are structurally related to paraherquamides and are thought to act by blocking cholinergic neuromuscular transmission.

References

  • Further novel metabolites of the paraherquamide family. Blanchflower S.E. et al., J. Antibiot. 1993, 46, 1355.
  • Anthelmintic paraherquamides are cholinergic antagonists in gastrointestinal nematodes and mammals. Zinser E.W. et al., J. Vet. Pharmacol. Ther. 2002, 25, 241.
  • Aspergillicins A-E: five novel depsipeptides from the marine-derived fungus Aspergillus carneus. Capon R.J. et al., Org. Biomol. Chem. 2003, 1, 1856.

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