Lydicamycin
Application Notes
Lydicamycin belongs to a novel structural class with highly selective antibiotic activity. Recent research has shown that lydicamycin and the related metabolites, TPU-0037A and TPU-0037C, are highly active against MRSA. Lydicamycin is also closely related to BN 4515N which was isolated from a strain of Microtetraspora as a neuritogenic agent.
References
- TPU-0037-A, B, C and D, novel lydicamycin congeners with anti-MRSA activity from Streptomyces platensis TP-A0598. Furumai T. et al., J. Antibiot. 2002, 55, 873.
- A new neuritogenetic compound BU-4514N produced by Microtetraspora sp. Toda S. et al., J Antibiot. 1993, 46, 875.
- Lydicamycin, a new antibiotic of a novel skeletal type. I. Taxonomy, fermentation, isolation and biological activity. Hayakawa Y. et al., J Antibiot. 1991, 44, 282.